E. Peter Geiduschek
نویسنده
چکیده
Peter Geiduschek was an undergraduate Chemistry major at Columbia University and received his Physical Chemistry Ph.D. at Harvard in 1952 for research under the direction of Paul Doty. After short stints teaching chemistry at Yale and the University of Michigan, and an early two-year sabbatical asa US Army draftee, he came to the University of Chicago's Committee on Biophysics, where he was first introduced to enzymology and to phage. In 1970, he joined the Department of Biology of the then relatively new University of California campus at La Jolla, and has remained at UCSD since. His research contributions have primarily dealt with mechanisms of transcription and gene regulation, pursued in the specific microbial context of phage-infected bacteria, eukaryotes (budding yeast and RNA polymerase III) and archaea.
منابع مشابه
Transcription: Adjusting to Adversity by Regulating RNA Polymerase
Under growth-limiting conditions, budding yeast shut down transcription of genes of the translation apparatus. Recent studies have shown that this response is signaled, in part, by multiple pathways that converge on Maf1, leading to a change of this protein's phosphorylation state and its relocation to the nucleus, where it represses RNA polymerase III.
متن کاملAn introduction to transcription and gene regulation.
Having been offered the opportunity to contribute one of the episodes of this series of personal-history accounts, I have chosen to write about circumstances that led me to the start of the scientific path that I have followed for the past 40-odd years. My account deals with a period of approximately six years and with events that I have written about recently (1); while I have been conscientio...
متن کاملOxygen consumption of isolated pancreatic islets of mice studied with the cartesian-diver micro-gasometer.
Eason, R., Cline, M. J. & Smellie, R. M. S. (1963). J. biol. Chem. 238, 3978. Eason, R. & Smellie, R. M. S. (1965). Biochem. J. 94, 7P. Geiduschek, E. P., Moohr, J. W. & Weiss, S. B. (1962). Proc. nat. Acad. Sci., Wash., 48, 1078. Geiduschek, E. P., Tocchini-Valentini, G. P. & Sarnat, M. T. (1964). Proc. nat. Acad. Sci., Wa8h., 52, 486. Green, M. H. (1964). Proc. nat. Acad. Sci., Wash., 52, 138...
متن کاملTechnology in response to local needs.
Science serves its readers as a forum for the presentaBef( tion and discussion of important issues related to the adfedera vancement of science, including the presentation of minority or conflicting points of view, rather than by pubwith p lishing only material on which a consensus has been and th reached. Accordingly, all articles published in Scienceincluding editorials, news and comment, and...
متن کاملDefining a bacteriophage T4 late promoter: bacteriophage T4 gene 55 protein suffices for directing late promoter recognition.
The RNA polymerase from bacteriophage T4-infected Escherichia coli, which specifically initiates transcription at phage T4 late promoters, is extensively modified by ADP-ribosylation of core subunits and by binding several virus-encoded subunits. We show here that one of these subunits, the phage T4 gene 55 protein, designated gp55, alone endows unmodified RNA polymerase core enzyme from uninfe...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Current Biology
دوره 20 شماره
صفحات -
تاریخ انتشار 2010